贫困和人类大脑之间的相互作用连接在整个寿命:一个系统的审查
Freek van der Heijden1, Nadya Ali1, Marion I van den Heuvel2
1Department of Cognitive Neuropsychology, Tilburg University, Warandelaan 2, Tilburg 5037 AB, the Netherlands; Zero Poverty Lab, Tilburg University, Warandelaan 2, Tilburg 5037 AB, the Netherlands.
贫困在整个发育过程中不同地影响大脑连接. 早期生活贫困可能会增加白质完整性,而后期阶段显示完整性下降和网络连接性改变,影响认知功能.
科学领域:
- 神经科学是一个神经科学.
- 发展心理学 发展心理学
- 社会经济研究 社会经济研究
背景情况:
- 贫困与认知和情绪缺陷有关.
- 大脑结构和功能组织的变化正在被研究为潜在的调解者.
研究的目的:
- 系统地审查和综合关于贫困与整个生命周期的大脑结构和功能连接的研究.
主要方法:
- 在Web of Science,PubMed,PsycINFO中进行系统的文献搜索 (2009-2024年).
- 包括检查结构性或静止状态功能连接和贫困的研究.
- 综合了59项符合条件的研究的结论.
主要成果:
- 婴儿期:与增加白质完整性相关的贫困 (结束,未结结).
- 童年以后:贫困与关键白质区域的完整性下降有关.
- 功能连接: 贫困与从童年开始在更高层次网络 (默认模式,前面对面,环眼) 的连接性降低有关.
- 边缘上层网络连接性随着年龄的增长而从负面转变为积极的关联.
结论:
- 贫困与整个发育过程中大脑连接体的显著改变有关.
- 贫困对大脑连接的影响是动态的,并且取决于阶段.
- 了解这些神经发育机制对于针对性干预来解决与贫困相关的差异至关重要.
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