在基于人口的综合分析中,生活方式,营养不良和健康风险之间的关联
Maxime A Banck1, Stephan H Bernhart2,3,4, Luise Müller1
1Medical Department III - Endocrinology, Nephrology, Rheumatology, University of Leipzig Medical Center, Leipzig, Germany.
Scientific reports
|December 20, 2025
概括
更健康的生活方式得分,反映了良好的饮食和运动习惯,与较低的心血管风险和营养不良有关. 整合生活方式因素可以改善风险检测和预防策略.
科学领域:
- 心血管疾病的研究研究.
- 营养科学 营养科学
- 公共卫生 公共卫生
背景情况:
- 肥胖,生活方式因素和营养不良是已知的心血管事件和死亡率的风险因素.
- 关于心血管健康的生活方式选择和营养状况之间的复杂相互作用仍然未被充分探索.
研究的目的:
- 在LIFE成人研究中调查更健康的生活方式得分 (LS) 与心血管风险 (弗雷明汉风险得分,FRS) 和死亡率之间的关联.
- 确定生活方式因素和营养不良的结合是否可以改善心血管风险的检测和预防.
主要方法:
- 在LIFE成人研究的6073名参与者中评估了生活方式评分 (LS).
- 使用多变量线性回归 (ANCOVA) 分析了与心脏代谢生物标志物和FRS的关联.
- 所有原因死亡率和营养不良指标 (CONUT,PNI,NRI) 在使用Cox模型的LS三角体中进行了分析.
主要成果:
- 较高的LS (表明较不健康的生活方式) 与增加的BMI和甘油三和降低的HDL相关.
- 营养不良随着LS的增加而减少,而FRS在不太健康的生活方式的人群中显著增加.
- 最不健康的LS的参与者表现出更高的全因死亡率,主要是由吸烟驱动的.
结论:
- 生活方式评分有效地通过代谢参数对健康状况进行分类.
- 将生活方式因素整合到临床诊断中,对于确定与心血管风险和营养不良的联系是有价值的.
- 改变生活方式是预防心血管疾病和改善整体健康状况的关键目标.
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