在精神病学试验中对自杀倾向的评估:范围审查的协议
Pascal Faltermeier1,2, Sophie Juul3,4,5, Faiza Siddiqui3
1Copenhagen Trial Unit, Centre for Clinical Intervention Research, The Capital Region, Copenhagen University Hospital - Rigshospitalet, Blegdamsvej 9, Copenhagen, 2100, Denmark. pascal.faltermeier@ctu.dk.
Systematic reviews
|December 20, 2025
概括
本范围审查检查了精神病随机临床试验如何评估自杀倾向,包括自杀思想和企图. 这些发现将指导未来的研究,研究心理健康试验中的患者重要结果.
科学领域:
- 精神病学是一个精神病学.
- 临床试验 临床试验
- 公共卫生 公共卫生
背景情况:
- 自杀是全球主要的死亡原因,特别影响患有心理健康障碍的人.
- 在精神病随机临床试验 (RCT) 中,评估自杀倾向对于患者安全和结果评估至关重要.
- 目前在心理健康RCT中评估自杀倾向的方法需要全面评估.
研究的目的:
- 进行范围审查,评估精神病学RCT中用于评估自杀念头,自杀未遂和自杀的方法.
- 识别和分析当代心理健康研究中如何衡量自杀倾向.
- 为改善精神病学研究中对患者重要结果的评估提供基础.
主要方法:
- 关于范围审查的议定书,在COMET网站上注册.
- 系统搜索自2022年1月以来发表的涉及心理健康患者的RCT的高影响期刊.
- 分析包括的RCT,以确定自杀念头,自杀企图和自杀的评估方法.
主要成果:
- 这次审查将是第一个系统地检查目前精神病学RCT中自杀倾向的评估.
- 调查结果将突出当前的做法和评估自杀结果的潜在差距.
- 该审查将提供关于不同心理健康干预措施中自杀性评估异质性的见解.
结论:
- 这一范围审查将为精神病学RCT中自杀倾向的评估提供关键的见解.
- 结果将为PIO-Psych倡议提供信息,指导未来的研究人员选择适当的患者重要结果.
- 该研究旨在通过标准化和改进心理健康试验中的自杀性评估来增强临床研究实践.
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