生物心理社会因素对 PrEP 摄入的影响在丹麦MSM中
Frederik Hyllested Birn1, Henrik Vardinghus-Nielsen2
1Department of Health Science and Technology, Master of Public Health Sciences & RN, Aalborg University, Selma Lagerløfs Vej 249, 9260, Aalborg, Gistrup, Denmark. frede-birn@hotmail.com.
AIDS and behavior
|December 21, 2025
概括
在丹麦,与男性发生性关系的男性 (MSM) 中,暴露前预防 (PrEP) 的吸收率很低. 对副作用的恐惧,医疗保健的耻辱感,以及对艾滋病毒的感知风险显著影响使用PrEP的意愿.
科学领域:
- 公共卫生 公共卫生
- 流行病学 流行病学
- 社会科学 社会科学 社会科学
背景情况:
- 暴露前预防 (PrEP) 是一种关键的艾滋病毒预防策略,特别是在与男性发生性关系的男性 (MSM) 中.
- 在全球和丹麦,MSM占艾滋病毒新增病例的很大比例.
- 尽管可用性和免费访问,但丹麦有资格的MSM中PrEP的使用率仍然很低,需要对障碍进行研究.
研究的目的:
- 调查影响丹麦MSM之间的PrEP意愿和吸收的生物心理社会因素.
- 确定阻碍符合条件的MSM群体采用PrEP的障碍.
主要方法:
- 在210名丹麦MSM中进行了在线横截面调查.
- 用后勤回归模型分析数据,以评估各种因素对PrEP使用和意愿的影响.
- 参与者通过社交媒体和艾滋病基金会诊所招募.
主要成果:
- 与使用者相比,非使用PrEP的人报告了更高的医疗保健系统污名化率 (OR 2.02) 和对副作用的恐惧 (OR 5.73).
- 在非使用者中,对副作用的高恐惧 (OR 2.00) 和高自我评估的艾滋病毒风险 (OR 5.60) 与更愿意使用PrEP有关.
- 40%的被调查的非使用者符合丹麦PrEP资格标准.
结论:
- 生物心理社会因素,包括对副作用的恐惧,感知到的艾滋病毒风险和医疗保健的耻辱感,显著影响了MSM中PrEP的吸收.
- 通过有针对性的公共卫生干预措施解决这些障碍对于增加PrEP使用率和减少艾滋病毒传播至关重要.
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