相关实验视频

Updated: Jan 8, 2026

A Whole Body Dosimetry Protocol for Peptide-Receptor Radionuclide Therapy PRRT: 2D Planar Image and Hybrid 2D+3D SPECT/CT Image Methods

A Whole Body Dosimetry Protocol for Peptide-Receptor Radionuclide Therapy PRRT: 2D Planar Image and Hybrid 2D+3D SPECT/CT Image Methods

Published on: April 24, 2020

[在前列腺癌生化复发后的18F-PSMA PET/CT成像]

Domonkos Nádasdy-Horváth¹, Márton Piroska¹, Sándor Czibor^1,2

¹1 Semmelweis Egyetem, Általános Orvostudományi Kar, Orvosi Képalkotó Klinika, Nukleáris Medicina Tanszék Budapest, Üllői út 26., 1085 Magyarország.

|December 21, 2025

概括

18F-JK-PSMA-7 PET/CT有效检测在 PSA 水平上升的患者中复发的前列腺癌. 较高的PSA水平显著提高了检测率,有助于对生化复发管理的临床决策.

科学领域:

核医学是一种核医学.
在瘤学瘤学.
放射性药物科学放射性药物科学

背景情况:

建议在前列腺切除术后生化复发时使用前列腺特异性膜抗原 (PSMA) PET/CT.
18F-JK-PSMA-7是一种新型的-18标记放射性药物,用于日常使用.
它在检测复发性前列腺癌中的临床适用性需要评估.

研究的目的:

评估18F-JK-PSMA-7 PET/CT用于检测前列腺癌复发的临床实用性.
评估PSA水平和PSA翻倍时间对检测率的影响.
为了将病变发病率与PSA值和PSA翻倍时间相关联.

主要方法:

对67名前列腺切除术后生化复发的患者进行了回顾性分析.
18F-JK-PSMA-7 进行PET/CT成像,检测PSA升高 (>0.2 ng/ml).
基于扫描前的PSA水平和PSA翻倍时间 (PSAdt) 的患者分层.

主要成果:

在76.1%的患者中检测到PSMA-avid病变.
在 PSA >1 ng/ml (88.1%) 的患者中,检测率明显高于 ≤1 ng/ml (56%) 的患者.
在阳性病例中,较高的PSA水平和较短的PSAdt与SUVmax的增加相关.

结论:

18F-JK-PSMA-7 PET/CT是识别复发前列腺癌的敏感工具.
扫描前的PSA水平是影响检测率和病变发病率的关键因素.
根据PSA水平对患者进行分层可以提高诊断产量并指导治疗决策.

关键词:

定子发射断层扫描 (PET).定位电子发射断层扫描.前列腺癌是前列腺癌.前列腺特异性膜抗原前列腺特异性膜抗原这就是为什么我们说"prosztatarákák".前列腺是特定的膜抗原.

更多相关视频

A New Technique for Treating Low-risk Prostate Cancer—Super Active Surveillance

A New Technique for Treating Low-risk Prostate Cancer—Super Active Surveillance

Published on: November 7, 2025

A Cognitive Fusion-guided Prostate Biopsy Using Multiparametric Magnetic Resonance Imaging and Transrectal Ultrasound

A Cognitive Fusion-guided Prostate Biopsy Using Multiparametric Magnetic Resonance Imaging and Transrectal Ultrasound

Published on: March 21, 2025

相关概念视频

Positron Emission Tomography

Positron Emission Tomography

Positron emission tomography (PET) is a medical imaging technique involving radiopharmaceuticals — substances that emit short-lived radiation. Although the first PET scanner was introduced in 1961, it took 15 more years before radiopharmaceuticals were combined with the technique and revolutionized its potential.
One of the main requirements of a PET scan is a positron-emitting radioisotope, which is produced in a cyclotron and then attached to a substance used by the part of the body...

Imaging Studies II: Positron Emission Tomography and Scintigraphy

Imaging Studies II: Positron Emission Tomography and Scintigraphy

Positron Emission Tomography (PET) is a medical imaging technique that provides crucial insights into the body's physiological functions at a molecular level. It is an indispensable resource for diagnosing, staging, and monitoring various illnesses, notably cancer, neurological disorders, and cardiovascular conditions.
Fundamental Principles of PET

Radiological Investigation III: Pulmonary Angiogram and PET Scan

Radiological Investigation III: Pulmonary Angiogram and PET Scan

Radiological investigations are paramount in the diagnosis and management of various pulmonary diseases. Two essential investigations are the Pulmonary Angiogram and the Positron Emission Tomography (PET) Scan.
Pulmonary Angiogram
A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...