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Updated: Jan 8, 2026

Development and Maintenance of a Preclinical Patient Derived Tumor Xenograft Model for the Investigation of Novel Anti-Cancer Therapies
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Development and Maintenance of a Preclinical Patient Derived Tumor Xenograft Model for the Investigation of Novel Anti-Cancer Therapies

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甲醇代谢物和酶因子通过抑制MAPK通路和降低PD-1表达的调节,影响结直肠癌的发展

Hanying Yi1, Yingying Dai1, Cuiyu Chen1

  • 1Department of Clinical Pharmacology, Xiangya Hospital, Central South University, China; National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, Hunan, China.

International immunopharmacology
|December 21, 2025
PubMed
概括

4-基醇,醇的代谢物,在结直肠癌中显示出比醇本身更强大的瘤抑制作用. 这种增强的效果与它对β-2上腺素受体 (β2-AR) 的更强的结合亲和力有关.

关键词:
4 - 基烯醇的使用.在AKT/MAPK路径中.结肠直肠癌是一种癌症.这种药物是propranolol.普罗普拉诺洛尔 (propranolol) 是一种抗体.

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