恶性征兆的每日大 (JIAD):一个系统的审查
Jessica Trac1, Rashi Ramchandani2, Pallavi Dutta3
1Department of Otolaryngology-Head and Neck Surgery, University of Toronto, Toronto, Ontario, Canada.
Oral oncology
|December 21, 2025
概括
牙在一天 (JIAD) 为头癌 (HNC) 患者提供成功的切除,重建和牙康复. 然而,辅助辐射增加了与骨质放射性死相关的假肢失败的风险,需要仔细的患者选择和风险益处讨论.
科学领域:
- 口腔和牙面部外科手术
- 在瘤学瘤学.
- 重建性手术是一种重建性手术.
背景情况:
- 牙在一天内 (JIAD) 结合了切除,大面部重建和立即的牙科康复.
- 在瘤群体,特别是头癌 (HNC) 中JIAD的证据有限.
- 这项研究系统地审查了HNC患者的JIAD结果.
研究的目的:
- 评估Jaw-in-a-day (JIAD) 程序在患有头癌 (HNC) 的患者中的有效性和结果.
- 为了评估假肢存活率,植入物骨整合和JIAD的HNC患者的并发症.
主要方法:
- 根据预先定义的协议 (PROSPERO CRD420251043510) 进行了系统审查.
- 在MEDLINE,Embase,CENTRAL,Web of Science和CINAHL (2013年1月至2025年10月) 上进行了搜索.
- 包括所有年龄段接受JIAD的HNC患者的研究;使用MINORS评估偏差风险.
主要成果:
- 包括57名HNC患者的9项研究;常见的诊断是下支骨状细胞癌.
- 全球普遍使用的无纤维板 (100%). 假肢存活率为78.1% (25/32),骨质放射性瘤 (ORN) 是切除的常见原因 (10.5%).
- 早期的植入物骨整合在照射部位是100%,但延迟的植入物失败发生在放射治疗领域的植入物中的11.1%.
结论:
- 一天内 (JIAD) 可以在精选的头癌 (HNC) 患者和缺陷中实现高成功率.
- 虽然早期的骨整合是有利的,但辅助放射治疗增加了ORN相关假肢失败的风险.
- 仔细考虑风险,益处和癌症分期对于JIAD中HNC患者的选择至关重要.
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