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Updated: Jan 8, 2026

Use of Hematopoietic Stem Cell Transplantation to Assess the Origin of Myelodysplastic Syndrome
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患有骨髓发育相关基因突变的急性髓性白血病患者可以从移植后的低甲基化剂维持中受益

Jiayu Huang1, Yi Xia2, Mengqi Xiang3

  • 1State Key Laboratory of Medical Genomics, Shanghai Institute of Hematology, National Research Center for Translational Medicine, Shanghai Rui Jin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

Transplantation and cellular therapy
|December 21, 2025
PubMed
概括

在全源干细胞移植后维持低甲基化剂 (HMA) 改善了具有不良风险的急性髓性白血病 (AML) 患者的生存率. 这种策略对患有骨髓质疏松症相关基因突变的人特别有益,但对无法检测到的MRD缓解期的患者可能不需要.

关键词:
急性骨髓性白血病 (AML) 是一种急性骨髓性白血病.全基性造血干细胞移植 造血干细胞移植低甲基化剂是一种低甲基化剂.维护处理 维护处理与骨髓质疏松症相关的基因突变.

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