针对性和个性化的饮食干预措施,用于肠-大脑相互作用障碍
Karen Routhiaux1, Tom van Gils2, Lukas Michaja Balsiger3
1Translational Research in Gastrointestinal Disorders TARGID, KU Leuven, Leuven Belgium.
Best practice & research. Clinical gastroenterology
|December 21, 2025
概括
饮食干预是管理肠-大脑相互作用障碍 (DGBI) 的关键. 研究正在探索个性化营养的生物标志物,指导哪些患者从特定饮食中获益最多.
科学领域:
- 胃肠病学 胃肠病学
- 营养科学 营养科学
- 心理学 心理学 心理学
背景情况:
- 肠-大脑相互作用障碍 (DGBI) 是常见的胃肠道疾病,严重影响患者的生活质量,并造成社会经济成本.
- 相当数量的DGBI患者将症状恶化与食物摄入联系起来,将饮食修改定位为主要的治疗途径.
- 当前的饮食策略往往涉及对可疑触发性食物的实证排除,目前正在进行的研究重点是确定特定的罪祸首营养素以实现个性化的方法.
研究的目的:
- 审查候选生物标志物的证据,旨在为DGBI提供个性化的饮食干预措施.
- 讨论已建立的实证饮食干预措施和专家营养师的作用.
- 确定可能从实证饮食干预中受益的患者个人资料,以及那些应该避免限制性饮食的患者.
主要方法:
- 文献综述和对DGBI饮食管理中的生物标志物现有研究的综合.
- 对已建立的实证饮食干预方案的分析.
- 对患者选择饮食疗法的临床指导.
主要成果:
- 目前正在调查几种候选生物标志物的证据,以促进DGBI的个性化营养.
- 经验性饮食干预,当由专家营养学家指导时,代表了一个有价值的管理策略.
- 特定的患者群体被确定为更有可能对实证饮食作出积极反应,而其他人可能需要不同的方法.
结论:
- 生物标志物研究有望为DGBI定制饮食干预措施提供希望.
- 专家营养师在成功实施饮食管理策略方面发挥着至关重要的作用.
- 谨慎的患者选择是最大限度地发挥实证饮食干预措施的好处,并避免限制性饮食的潜在危害至关重要.
更多相关视频
相关概念视频
Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy
614
Various diagnostic tests are employed in the diagnostic process for Inflammatory Bowel Disease (IBD), particularly to differentiate between Crohn's disease and ulcerative colitis.
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
614
Taste Buds and Receptors
4.5K
Gustation, or the sense of taste, is intrinsically linked to the anatomical structures located on the tongue. This organ's surface, along with the entirety of the oral cavity, is adorned with stratified squamous epithelium. Evident on the tongue are elevated structures known as papillae (singular = papilla), which house the mechanisms for the transduction of gustatory stimuli. Four distinct types of papillae exist, each identified by their unique morphological attributes: the circumvallate,...
4.5K
Irritable Bowel Syndrome III: Medical and Nursing Management
613
Managing Irritable Bowel Syndrome (IBS) involves a multifaceted approach, including lifestyle modifications, dietary changes, and medication.
613
Chronic Bowel Disorders: Introduction
732
Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
732
Physiology of Enteric Nervous System and Gut Health
834
The gastrointestinal tract, responsible for the digestion and absorption of nutrients, is safeguarded by the intestinal barrier, which consists of secretory, physical, and immune components. At the forefront is the secretory barrier, composed of essential elements such as mucus, gut microbiota, and defense proteins. They collaborate to break down food particles, facilitate nutrient absorption, and maintain optimal gut health. These secretory components ensure the smooth functioning of the...
834
Binge Eating Disorders
402
Binge eating disorder is a significant mental health condition characterized by recurrent episodes of excessive food consumption within a short period, accompanied by a perceived loss of control over eating behavior. Unlike occasional overeating, binge eating disorder is marked by distressing emotions such as guilt, shame, and anxiety following binge episodes. The disorder affects individuals across different ages and backgrounds, with profound implications for physical and psychological...
402


