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Updated: Jan 8, 2026

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YTHDF1通过抑制结直肠癌中NOTCH1诱导的干性来向化疗反应

Henley Cheung1, Huarong Chen1,2, Danyu Chen1

  • 1Institute of Digestive Disease and Department of Medicine and Therapeutics, State Key Laboratory of Digestive Disease, Li Ka Shing Institute of Health Sciences, CUHK-Shenzhen Research Institute, The Chinese University of Hong Kong, Hong Kong SAR, China.

Signal transduction and targeted therapy
|December 21, 2025
PubMed
概括

m6A阅读器YTHDF1通过激活NOTCH1信号来驱动结直肠癌 (CRC) 干细胞和化学抵抗. 向YTHDF1提供了一种有希望的策略,以提高CRC患者的化疗疗效率.

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