在患有系统性红斑狼的成年人中尿失禁
Gabriel Salazar1, Scott Bauer1,2,3, Courtney Hoge4
1Department of Medicine, University of California, San Francisco.
ACR open rheumatology
|December 21, 2025
概括
尿失禁 (UI) 影响了超过三分之一的全身性红斑狼 (SLE) 患者,并且与更高的疾病活性有关. 早期查和管理对这一群体至关重要.
科学领域:
- 类风湿病学 类风湿病学
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 流行病学 流行病学
背景情况:
- 尿失禁 (UI) 的患病率和对系统性红斑狼 (SLE) 的影响尚未得到充分证实.
- 了解SLE的UI对于改善患者护理和生活质量至关重要.
研究的目的:
- 为了确定UI在美国SLE队列中的患病率和生命负担.
- 调查UI和SLE疾病活动和损伤之间的关联.
主要方法:
- 一组425名SLE患者 (平均年龄46.3岁,92.0%为女性) 填写了UI评估问卷.
- 测量了SLE活动和损伤,后勤回归分析了与UI的关联.
- UI被定义为每月的尿泄漏;疾病指标在中位数被二分化.
主要成果:
- 36.2%的SLE患者报告每月一次UI,混合型是最常见的.
- 在女性,老年人和肥胖者中,UI更为普遍.
- 较高的SLE疾病活动显著增加了UI几率 (OR=3.02);疾病损伤显示出非显著的趋势.
结论:
- UI是SLE患者常见的病症,与疾病活性增加显著相关.
- 这些发现强调了需要更新临床查和SLE中UI的管理协议.
- 解决UI可以改善SLE患者的日常生活和整体健康结果.
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