较高的心血管风险因素负担与累积脑震荡史和年龄相关差异相关
Benjamin L Brett1, Mikaela E Sullivan, Neelum T Aggarwal
1Author Affiliations: Department of Neurosurgery, Medical College of Wisconsin, Milwaukee, Wisconsin (Dr Brett, Ms Sullivan, and Dr McCrea); Department of Neurological Sciences, Rush Alzheimer's Disease Center, Chicago, Illinois (Dr Aggarwal); Department of Exercise and Sport Science, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina (Drs Kerr and DeFreese); Datalys Center for Sports Injury Research and Prevention, Indianapolis, IN (Dr Chandran); Department of Physical Medicine & Rehabilitation, Virginia Commonwealth University, Richmond, Virginia (Dr Walton); Institute for Women's Health, Virginia Commonwealth University, Richmond, Virginia (Dr Walton); Department of Kinesiology, Michigan State University, East Lansing, Michigan (Dr Guskiewicz); Psychological and Neurobehavioral Associates, Inc., State College, Pennysylvania (Dr Echemendia); Boston Children's Hospital, Boston, Massachusetts (Drs Meehan and Mannix); Department of Pediatrics and Orthopedics, Harvard Medical School, Boston, MA (Dr Meehan); and Department of Pediatrics and Emergency Medicine, Harvard Medical School, Boston, MA (Mannix).
经常性脑震荡与心血管问题有关,特别是在年轻的前运动员中. 对于有脑震荡史的运动员来说,早期查和心血管风险因素的管理至关重要.
科学领域:
- 神经学 神经学
- 心脏病学 心脏病学
- 运动医学 运动医学
背景情况:
- 经常性脑震荡可能会导致通过心血管功能障碍的长期不良结果.
- 脑震荡史的早期发病增加了这些结果的风险.
研究的目的:
- 研究脑震荡史和年龄对心血管风险因素 (CRF) 患病率的相互作用.
- 研究前职业足球运动员不同年龄段的CRF和多领域功能之间的关联.
主要方法:
- 利用了来自前国家足球联盟 (NFL) 球员的调查数据.
- 将二分化参与者分为年轻 (≤50岁) 和年长 (>50岁) 的年龄组.
- 使用后勤和线性回归来分析相互作用和关联,评估CRF (高血压,高脂血症,糖尿病,睡眠呼吸暂停) 和临床结果 (抑郁症,焦虑症,认知功能,情绪和行为失控).
主要成果:
- 对于高血压和高脂血症,发现脑震荡史和年龄之间的显著相互作用,年轻运动员患有更多脑震荡的诊断更高.
- 睡眠呼吸暂停的患病率随着脑震荡病史增加,不论年龄.
- CRF,特别是高血压和高脂血症,与年轻的前球员更高的症状认可有关.
结论:
- 心血管健康是连接经常性脑震荡与前接触体育运动员不良长期结果的重要途径.
- 这些发现支持了早期查和对有大量脑震荡病史的运动员进行CRF治疗的必要性.
- 建议采取积极的临床方法,以减轻与脑震荡史相关的长期健康风险.
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