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在1型糖尿病的心脏代谢风险因素中,与肥胖和超重相关的差异
Adnan S Syed1, Gayatri Arani1,2, Sharon Macwan1
1Phoenix VA Health Care System, Phoenix, Arizona, USA.
超重和肥胖症在1型糖尿病 (T1D) 的退伍军人中正在增加,这与更糟糕的心脏代谢健康有关. 这些发现强调了迫切需要在这个人群中制定有效的体重管理策略.
科学领域:
- 心脏病学 心脏病学
- 内分泌学 在内分泌学.
- 公共卫生 公共卫生
背景情况:
- 1型糖尿病 (T1D) 的管理需要注意体重和心脏代谢风险.
- 患有T1D的退伍军人代表了研究这些因素的独特人群.
研究的目的:
- 确定患有T1D的退伍军人中超重和肥胖的患病率.
- 调查这个群体中体重状况和心脏代谢风险因素之间的关联.
主要方法:
- 对21至75岁的T1D患者的退伍军人卫生管理局数据的分析.
- 从2016-2023年评估体重类别和心脏代谢风险因素.
- 根据基线特征,年龄,性别和种族/民族的统计调整.
主要成果:
- 在2022-2023年,超重和肥胖分别影响了39.7%和32.4%的T1D退伍军人.
- 自2016年以来,患病率稳步增加,特别是在年轻人中 (21-39).
- 较高的体重类别与较差的心脏代谢风险因素 (血压,脂质,EGFR) 相相关,观察到年龄-BMI相互作用.
结论:
- 肥胖在成年T1D退伍军人中普遍存在并日益增加.
- 肥胖与T1D退伍军人的不良心脏代谢风险因素密切相关.
- 更好地了解体重增加机制和增强体重管理至关重要.
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