低前切除综合征的评估和管理
Samantha M Linhares1, Anne K Mongiu1
1Division of Colon and Rectal Surgery, Department of Surgery, Yale School of Medicine, New Haven, Connecticut.
Clinics in colon and rectal surgery
|December 22, 2025
概括
低前切除综合征 (LARS) 在直肠癌手术后引起了重大的生活质量问题. 本综述评估了LARS评估工具和治疗方法,强调了对标准化护理和进一步研究的需要.
科学领域:
- 结肠直肠手术 结肠直肠手术
- 胃肠病学 胃肠病学
- 在瘤学瘤学.
背景情况:
- 低前切除综合征 (LARS) 是直肠癌手术后的一种常见,使人衰弱的疾病.
- 症状包括肠道失禁,紧迫性和集群性,显著影响患者的生活质量.
- 高达80%的患者患有LARS,需要有效的管理策略.
研究的目的:
- 审查和评估LARS目前的评估工具.
- 探索LARS.的既定和新兴治疗方案.
- 评估支持不同LARS管理策略的证据.
主要方法:
- 关于LARS评估和治疗的综合文献综述.
- 包括到2024年的正在进行的临床试验.
- 对诊断工具和治疗干预措施的分析.
主要成果:
- 最近对LARS的定义进行了修订,但验证的诊断工具落后.
- 概述了一种分层治疗方法:优化肠道习惯,饮食变化和药物 (一线);骨盆底康复或过灌 (二线);神经调节或口腔形成 (三线).
- 支持当前策略的证据需要进一步细化.
结论:
- LARS是一种复杂的疾病,在一致的评估和有效的治疗方面存在挑战.
- 有机会标准化手术前教育,评估和治疗升级.
- 进一步研究心理社会支持和明确的治疗算法至关重要.
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