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标准化金科比洛巴提取物 (EGb 761) 用于膝关节骨关节炎:叙述性审查

Yunqing Wang^1,2, Ziyu Liu^1,2, Yong Liu¹

¹Department of Traumatic Orthopedics, Affiliated Hospital of Shandong Second Medical University, Weifang, 261031, People's Republic of China.

Drug design, development and therapy

|December 22, 2025

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银杏花提取物 (EGb 761) 通过减少炎症和改善功能,显示出对膝关节骨关节炎 (KOA) 的潜力. 然而,需要更多高质量的试验来确认它对KOA患者的治疗益处.

科学领域:

整形外科和运动医学
药理学和制药科学药理学和制药科学
自然产品研究自然产品研究

背景情况:

膝关节骨关节炎 (KOA) 是一种衰弱的退行性关节疾病,治疗选择有限.
银杏花提取物 (EGb 761) 具有抗炎,抗氧化和肌肉保护性质.

研究的目的:

审查目前关于EGb 761在膝关节骨关节炎治疗潜力的证据.
评估EGb 761作为KOA的辅助疗法,考虑到其多目标药理作用.

主要方法:

在KOA中对EGb 761进行实验和临床研究的叙述性综述.
在PubMed,Scopus和Web of Science进行的文献搜索到2025年.

主要成果:

临床前和临床数据表明EGb 761可能会降低KOA中的炎症,氧化应激和状细胞亡.
观察到缓解疼痛和关节功能的适度改善,具有有利的安全性.

结论:

目前的证据表明,EGb 761可能为KOA提供一些好处,但研究结果因研究质量和规模而受到限制.
需要进一步进行高质量的随机对照试验,以最终确定EGb 761对膝关节关节炎的疗效.

关键词:

第761章没有了科亚科亚是什么意思有效性和治疗效果.银杏罗巴提取物银杏罗巴提取物膝盖骨关节炎膝盖骨关节炎

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