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Updated: Jan 8, 2026

An Immunofluorescent Method for Characterization of Barrett’s Esophagus Cells
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DADS通过抑制RORα/β-通过PKCα-依赖酸化在胃癌中抑制RORα/β-通过PKCα-依赖酸化来调节EMT和化疗抵抗

Yizhen Zhang1,2, Juan Li1,3, Huanqing Liu1,4

  • 1Hunan Province Key Laboratory of Cancer Cellular and Molecular Pathology, Cancer Research Institute, University of South China, Hengyang, 421001, China.

Oncology research
|December 22, 2025
PubMed
概括

迪亚利二硫化物 (DADS) 通过向PKCα/RORα通路来抑制胃癌 (GC) 的进展,减少入侵和EMT,同时增强5-FU灵敏度. 这表明DADS是GC治疗的潜在RORα激动剂.

关键词:
迪亚利尔二硫化物.药物耐药性 耐药性 药物耐药性表皮细胞-介质细胞过渡.胃癌细胞 胃癌细胞与视网膜相关的孤儿受体α (RORα) /β-catenin信号传递.

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