患有下痢症的患者自伤风险:基于人口的队列研究
Wai Kwong Tang1, Kelvin K F Tsoi2,3, Terry Cheuk Fung Yip4
1Department of Psychiatry, The Chinese University of Hong Kong, Hong Kong, Hong Kong SAR, China.
Frontiers in psychiatry
|December 22, 2025
概括
那些被诊断出患有下体质症 (HYPO) 的人并没有面临更高的自我伤害行为风险. 这项大规模研究发现,HYPO患者与普通人群之间的自我伤害率没有显著差异.
科学领域:
- 精神病学和心理学 精神病学和心理学
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 抑郁症 (现在被称为疾病焦虑障碍) 具有过度担心患有或发展严重疾病的特点.
- 之前的研究还没有明确确地确定患有阴性质症的个体是否有自我伤害行为的风险增加.
研究的目的:
- 为了调查下症 (HYPO) 的诊断和参与自我伤害行为的风险之间的关联.
- 将HYPO患者的自我伤害发病率与匹配的对照组进行比较.
主要方法:
- 一个匹配的队列研究,利用香港公共医院的电子健康记录 (1993-2022).
- 确定了906名HYPO患者和906名匹配的对照.
- 用考克斯回归和竞争性风险分析,对自我伤害诊断,死亡或研究结束 (2023) 的参与者进行了跟踪.
主要成果:
- 在30年内,5.6%的HYPO组和5.4%的对照组表现出自我伤害行为.
- 自伤的发生率为 43.4/10,000人年 (HYPO) 与 38.2/10,000人年 (对照) 相比.
- 在HYPO组中,自我伤害的调整后危险和次危险比分分别为0.87和0.84,没有统计学意义 (p=0.474).
结论:
- 这项研究没有发现任何有意义的证据来支持在被诊断为患有下痢症的个体中自我伤害的风险增加.
- 建议进行进一步的研究来证实这些发现,并探索这种人群中自我伤害的潜在独特风险因素.
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