在患有CKD的儿童中,酸盐控制的障碍和促进因素
Louise McAlister1, Vanessa Shaw2, Pearl Pugh3
1Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK.
Kidney international reports
|December 22, 2025
概括
在儿科慢性病 (CKD) 中,对酸盐控制的坚持受到社会和实际障碍的阻碍,而不仅仅是知识差距. 个性化策略是改善患有CKD儿童管理的关键.
科学领域:
- 儿科脏病学 儿科脏病学
- 矿物质和骨疾病管理管理
- 慢性病 (CKD) 研究研究
背景情况:
- 在儿科慢性病 (CKD) 中治疗矿物质和骨疾病需要控制血清酸盐水平.
- 超酸血症在患有慢性病的儿童中普遍存在,特别是青少年,这是由于对酸盐结合剂和饮食限制的不理想坚持.
研究的目的:
- 探索患有CKD的儿童及其照顾者的酸盐相关知识和坚持障碍.
- 确定影响酸盐管理策略的因素.
主要方法:
- 一项连续的解释性混合方法研究,涉及患有CKD 4-5阶段的儿童 (8-18岁) 和他们的护理人员.
- 酸盐知识使用酸盐理解和知识评估问卷进行评估.
- 通过在线焦点小组探索对酸盐控制的现实挑战.
主要成果:
- 儿童和护理人员的知识分数均为中等,年龄较大的儿童得分更高,但知识与血清酸盐水平没有相关性.
- 饮食限制被认为比酸盐结合剂药物坚持更具挑战性.
- 焦点小组的主要主题包括实践建议的价值,对个性化策略的偏好,社会环境的破坏以及教育和自我管理技能的重要性.
结论:
- 在儿科CKD中对酸盐管理的不良遵守更多地源于社会和实际障碍,而不是知识缺陷.
- 研究结果表明,解决这些现实世界的挑战的个性化策略对于改善儿科CKD患者的坚持是必不可少的.
相关概念视频
Chronic Kidney Disease III: Interprofessional Care
320
Chronic kidney disease (CKD) requires collaborative and comprehensive management. CKD progresses through stages and can lead to end-stage kidney disease (ESKD) if untreated. Interprofessional collaboration and patient education are crucial, enabling patients to manage their health and improve their quality of life.Diagnostic approach for chronic kidney diseaseThe diagnosis of CKD primarily focuses on the glomerular filtration rate (GFR), which assesses kidney function by measuring how well...
320
Roles of Electrolytes: Calcium and Phosphate
1.1K
Calcium and phosphate are essential electrolytes in the human body, with calcium being the most abundant mineral. Around 99% of the body's calcium is stored in the skeleton and teeth, forming a crystal lattice of mineral salts in combination with phosphates. Calcium plays crucial roles in various bodily functions such as blood clotting, neurotransmitter release, muscle tone maintenance, and nervous and muscle tissue excitability.
The calcium concentration in blood plasma is primarily...
The calcium concentration in blood plasma is primarily...
1.1K
Chronic Kidney Disease II: Clinical Manifestations
522
Chronic Kidney Disease (CKD) progressively impairs multiple body systems due to the accumulation of uremic toxins, which disrupt cellular functions across various organs.Neurologic symptomsNeurologic symptoms often arise early in CKD, as uremic toxin buildup drives changes in cognitive and motor functions. Patients frequently experience fatigue, headache, confusion, difficulty concentrating, and, in severe cases, seizures. Peripheral neuropathy commonly manifests as burning sensations in the...
522
Pharmacokinetics in Pediatric Patients: Drug Excretion
194
In pediatric medicine, understanding the renal function and drug elimination nuances is crucial for administering safe and effective treatments. Newborns, in particular, display markedly slower renal functions than adults, profoundly affecting how drugs are cleared from their bodies. This slower drug clearance requires clinicians to extend the dosing intervals for many medications to prevent drug accumulation and toxicity while ensuring therapeutic efficacy.One key area where these adjustments...
194
Peritoneal Dialysis III: Nursing Management
592
Peritoneal dialysis, or PD, utilizes the peritoneal membrane as a filter to eliminate excess fluid and waste products. Effective nursing management is essential for ensuring patient safety, preventing complications, and promoting optimal function of the peritoneal dialysis process.Assessment and MonitoringNurses must thoroughly assess the patient before, during, and after each dialysis session. Regular monitoring includes vital signs, daily weight, fluid intake and output, and laboratory values...
592
Chronic Kidney Disease IV: Nursing Management
296
Nursing management is essential for preventing complications, maintaining stability, and improving patients' quality of life in chronic kidney disease (CKD). By using a structured approach, nurses help slow CKD progression and support effective patient care.1. Comprehensive patient assessmentEffective management begins with nurses reviewing the patient’s medical history, and identifying key risk factors like diabetes, hypertension, and nephrotoxic drug use. Nurses assess signs of...
296


