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80岁以上患者放射治疗实践的评估:一项回顾性研究
Harun Demir1, İbrahim Babalıoğlu1, İlyas Akkar2
1Department of Radiation Oncology, Konya City Hospital, Konya, Turkey.
South Asian journal of cancer
|December 22, 2025
概括
放射治疗 (RT) 对老年癌症患者 (≥80岁) 是安全有效的,用于治疗和息护理. 诸如绩效状况和合规性等因素会影响这一群体的生存结果.
科学领域:
- 老年瘤学 老年瘤学
- 辐射瘤学 辐射瘤学
- 临床癌症研究 临床癌症研究
背景情况:
- 癌症发病率随着年龄的增长而增加,这给老年人群 (≥80岁) 的治疗带来了独特的挑战.
- 放射治疗 (RT) 是癌症治疗的基石,但其在老年人中的应用和结果需要具体的评估.
研究的目的:
- 评估接受放射治疗的80岁及以上的癌症患者的生存结果,预后因素和治疗遵从性.
- 为了确定RT的安全性和有效性,在这个特定的老年人群中,对于息和治愈的意图.
主要方法:
- 在2021年8月至2024年5月期间接受RT治疗的76名80岁以上患者的回顾性分析.
- 从医疗记录中收集和审查患者人口统计数据,瘤特征,RT细节和生存数据.
主要成果:
- 总生存时间 (OS) 的中位数为10个月,治疗疗法 (25.1个月) 与息性RT (7.2个月) 的总生存时间明显更长.
- 性能状况差,RT前白细胞计数,服从性和住院状况与治疗组的生存率下降有关;类似的因素加上远程复发影响了息组.
- 观察到高治疗顺应率 (69.7%),特别是在接受门诊治疗的良好表现状态的患者中. 没有报告高度 (3-4) RT毒性.
结论:
- 放射治疗是一种有效和安全的治疗方式,用于80岁及以上的癌症患者的息和治愈治疗.
- 建议进行进一步的多中心研究,以验证这些发现,并优化患者选择,以改善这一年龄组的治疗结果.
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