印度高级/转移性结肠直肠癌临床实践的共识陈述,使用修改的德尔菲方法
Anant Ramaswamy1, Sujay Srinivas2, Viraj Lavingia3
1Department of Medical Oncology, Tata Memorial Hospital (Homi Bhabha National Institute), Mumbai, Maharashtra India.
South Asian journal of cancer
|December 22, 2025
概括
这项研究为印度的转移性结直肠癌 (mCRC) 管理提供了基于证据的指导方针. 它解决了瘤学家治疗晚期结直肠癌所面临的独特挑战和资源限制.
科学领域:
- 在瘤学瘤学.
- 胃肠病学 胃肠病学
背景情况:
- 结肠直肠癌 (CRC) 是全球普遍存在的恶性瘤,也是印度男性第四常见的癌症 (GLOBOCAN 2020).
- 大约30%的患者患有晚期或转移性结直肠癌 (mCRC).
- 本出版物解决了在印度医疗保健领域管理mCRC的具体挑战.
研究的目的:
- 总结针对印度环境的mCRC管理的最新证据.
- 为治疗mCRC的医疗瘤学家制定共识陈述,考虑独特的国家挑战.
- 专注于对mCRC的识别,管理和系统治疗方法.
主要方法:
- 一个由38名医疗瘤学家组成的小组于2023年2月召开会议.
- 证据审查的重点是mCRC的识别,管理和系统疗法.
- 共识陈述是使用文献审查来制定的,并通过修改后的Delphi方法进行评估.
主要成果:
- 为管理mCRC而制定了51个共识陈述,包括寡头转移和不可切除的病例.
- 这些陈述涵盖了各种全身治疗选择.
- 考虑了资源有限的场景,包括经济因素和印度的药物供应.
结论:
- 这些共识声明为印度的mCRC治疗提供了实际的,基于证据的指导方针.
- 对于资源有限的环境,建议是分层的.
- 这些指导方针旨在改善印度晚期结直肠癌的管理.
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