调节代谢健康和生理功能:针对肠道微生物群的饮食干预措施的进展
Syed Arman Rabbani1, Mohamed El-Tanani1, Miodrag Janić2,3,4
1RAK College of Pharmacy, RAK Medical and Health Sciences University, Ras Al Khaimah, United Arab Emirates.
Therapeutics and clinical risk management
|December 22, 2025
概括
肠道微生物群 (GM) 显著影响宿主代谢健康和恒温. 饮食干预可以调节GM以对抗代谢综合征 (MetS) 并改善整体健康.
科学领域:
- 微生物学 微生物学
- 人体生理学 人体生理学
- 营养科学 营养科学
背景情况:
- 人的肠道拥有一个复杂的微生物群落,对宿主代谢过程至关重要.
- 肠道微生物群 (GM) 影响能量吸收,食欲,葡萄糖/脂质新陈代谢和肝脏脂肪储存,维持平衡.
- 生物失调症或转基因破坏与代谢综合征 (MetS),糖尿病,肥胖和心血管疾病 (CVD) 有关.
研究的目的:
- 综合有关肠道微生物群,代谢功能和饮食干预之间的相互作用的当前知识.
- 提供基于证据的概述GM在MetS病原体和潜在治疗策略中的作用.
- 探索营养干预如何调节转基因,改善代谢健康.
主要方法:
- 在PubMed,Scopus,科学网和谷歌学者中索引的研究的叙事综述.
- 关键词包括:肠道微生物群,代谢综合征,饮食,失生症.
- 临床和临床前研究结果的整合.
主要成果:
- 转基因生物在宿主代谢健康和恒温中起着至关重要的作用.
- 失生症与MetS,糖尿病,肥胖和心血管疾病的进展有关.
- 饮食干预显示了调节转基因生物的潜力,以减轻失生症并支持代谢健康.
结论:
- 了解转基因在MetS病变发生中的作用,为治疗提供了有前途的途径.
- 营养策略可以支持有益的肠道细菌,减轻肠道疾病.
- 基于个体微生物群概况的个性化营养干预措施代表了改善代谢健康的未来方向.
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