预测模型的延迟的低血症后,内内性透视切除后的垂体腺瘤预测模型
Hangyi Tan1, Xianlong Miao1, Yukang Pei1
1Department of Neurosurgery, Department of Skull Base Oncology, Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu, China.
Frontiers in human neuroscience
|December 22, 2025
概括
这项研究确定了脑下垂体手术后延迟低血症的关键危险因素. 使用这些因素的预测模型可以帮助识别患有这种并发症高风险的患者.
科学领域:
- 神经外科 神经外科
- 内分泌学 在内分泌学.
- 医学统计 医学统计
背景情况:
- 内镜内性透切除是对垂体腺瘤的常见程序.
- 延迟性低血是一种潜在的术后并发症.
- 准确的风险分层对于患者管理至关重要.
研究的目的:
- 为了确定垂体腺瘤切除后延迟低血症 (DPH) 的危险因素.
- 开发和验证DPH的预测模型.
主要方法:
- 追溯分析155名接受了垂体腺瘤切除的患者.
- 后勤回归分析以确定风险因素.
- 使用R软件开发和验证一个预测模型.
主要成果:
- 确定了关键的危险因素:手术前益生菌素升高,超细胞水库高度更高,以及早期术后低血.
- 预测模型表现强 (训练中的AUC为0.943,验证中的AUC为0.959).
- 决策曲线分析表明了临床效用.
结论:
- 开发了一个强大的DPH预测模型.
- 诺米图谱有助于早期识别高风险患者.
- 这种工具可以改善临床决策和患者的治疗结果.
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