结合性肺纤维化和肺气:一个叙事性回顾
Wenjing Zeng1, Binmiao Liang1, Xuemei Ou1
1Department of Pulmonary and Critical Care Medicine, West China Hospital, Sichuan University, Chengdu, China.
Frontiers in medicine
|December 22, 2025
概括
结合性肺纤维化和肺气 (CPFE) 由于相反的特征而带来诊断挑战. 本综述综合了关于CPFE的文献,涵盖了其诊断,预后和管理.
科学领域:
- 肺部病理学 肺部病理学
- 放射学 放射学是一门学科.
- 病理生理学 病理生理学
背景情况:
- 结合性肺纤维化和肺气 (CPFE) 是上叶肺气和下叶纤维化的综合症.
- 由于对立的病理生理学效应掩盖特征,诊断很困难.
- 标准化术语存在,但诊断标准和管理策略尚未建立.
研究的目的:
- 综合关于结合性肺纤维化和肺气 (CPFE) 的当前文献.
- 涵盖历史背景,流行病学,致病性,临床表现,诊断特征,疾病过程和CPFE的管理.
主要方法:
- 从1990年到2024年的文学叙事综述.
- 综合了关于CPFE临床,放射和生理方面的信息.
主要成果:
- 与COPD或IPF患者相比,CPFE患者的生存率降低,死亡率更高.
- 疾病的严重程度 (CT检测结果),年龄和诸如肺癌和肺动脉高血压等并发症都导致了不良结果.
- 尽管标准化了术语,但诊断方面的挑战仍然存在.
结论:
- CPFE是一种明显的临床-放射-生理综合征,具有显著的死亡率.
- 为了统一的诊断标准和最佳的管理策略,需要进一步的研究.
- 了解CPFE的复杂性对于改善患者治疗结果至关重要.
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