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维生素D水平与妊娠高血压疾病之间的关联

Krishnanand Ps¹, Sangeeta B Singh², Shikhaa Mahajan²

¹Biochemistry, Amrita Institute of Medical Sciences and Research Center, Faridabad, IND.

|December 22, 2025

概括

低维生素D水平与更严重的妊娠高血压障碍有关,包括先兆子和后兆子. 这表明维生素D可能在预防这些严重的妊娠并发症方面发挥作用.

科学领域:

产科和妇科产科和妇科
内分泌学在内分泌学.
营养科学营养科学

背景情况:

怀孕期间的高血压,包括产前,对母亲和胎儿的健康构成重大风险.
维生素D缺乏症在包括印度在内的亚洲孕妇中很常见.
维生素D在胎盘功能中的作用及其与妊娠高血压障碍的潜在联系需要调查.

研究的目的:

调查维生素D水平与妊娠高血压疾病之间的关联.
为了比较怀孕妇女的维生素D水平,有和没有高血压疾病.
探索维生素D水平与高血压疾病的严重程度之间的相关性.

主要方法:

一项涉及300名孕妇的横截面研究 (150例高血压病例,150例正常血压对照).
病例被分为没有严重特征的先兆子症,具有严重特征的先兆子症和先兆子症.
使用竞争性酶相关免疫吸收试验 (ELISA) 量化维生素D水平.

主要成果:

在所有组中观察到维生素D平均水平的显著差异 (p = 0.0001).
孕患者的维生素D水平平均最低 (8.73 ± 5.10 ng/mL),其次是重度孕和轻度孕.
在高血压疾病的严重程度和维生素D水平之间发现了强烈的负相关性 (r = -0.6159,p < 0.0001).

结论:

较低的血清维生素D水平与怀孕期间高血压疾病的严重程度增加有关.
这些发现凸显了维生素D对与怀孕相关的严重高血压的潜在保护作用.
建议对维生素D补充剂进行进一步的研究和评估,以改善母亲和胎儿的结果.

关键词:

调节血压调节血压的方法孕期高血压疾病 (HDP)孕产妇健康孕产妇健康产前 - 产后 - 产前维生素D水平维生素D水平

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