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延迟爆发和怀孕结果在单个冷解的欧普洛伊德胚胎细胞移植中
Jingwen Lang1,2, Ling Hong1,2, Wanli Yang1,2
1Department of Assisted Reproductive Medicine, Shanghai First Maternity and Infant Hospital, School of Medicine, Tongji University, Shanghai, China.
Frontiers in endocrinology
|December 22, 2025
概括
与第6天的胚胎相比,第5天的欧类胚胎囊提供了更好的植入率和活产率,特别是在老年女性中. 发育速度显著影响结果,特别是低质量的胚胎.
科学领域:
- 生殖医学 生殖医学
- 胚胎学 胚胎学
- 遗传学 遗传学是一种遗传学.
背景情况:
- 胚胎发育速度是辅助生殖技术的一个关键因素.
- 评估发育时间对欧卵母细胞转移结果的影响对于优化生育治疗至关重要.
研究的目的:
- 评估胚胎发育速度 (第5天和第6天) 对欧卵母细胞移植的临床结果的影响.
- 研究发育速度,母亲年龄和胚胎形态质量之间的相互作用.
主要方法:
- 单个欧卵母细胞移植的回顾性队列研究.
- 胚胎按发育日 (第5天和第6天) 分类.
- 按母亲年龄和胚胎形态分层进行结果分析.
主要成果:
- 第五天的欧卵性母细胞囊的植入率 (68.8%与48.3%) 和活产率 (63.7%与40.4%) 比第六天要高得多.
- 在先进的母亲年龄组中,第5天的胚胎产生了更高的植入率 (72.5%与40.5%) 和活产率 (68.8%与28.6%).
- 发育速度影响了低质量的胚胎的结果,第5天显示出更好的活产率 (65.5%vs29.3%).
结论:
- 与第6天相比,第5天的胚胎与更好的妊娠结果有关,特别是在老年妇女和质量较低的胚胎中.
- 虽然第5天的胚胎显示出更好的结果,但第6天的胚胎胚胎移植仍然提供了可接受的结果.
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