癌症患者的有效戒烟干预措施:随机对照试验的系统审查和元分析
Livingstone Aduse-Poku1, Hui G Cheng1, Oxana Palesh2
1Massey Comprehensive Cancer Center, Virginia Commonwealth University, Richmond, United States.
Tobacco prevention & cessation
|December 22, 2025
概括
戒烟干预措施显著提高了癌症患者戒烟率. 结合药理和行为方法是最有效的成功戒烟在这个人群.
科学领域:
- 在瘤学瘤学.
- 公共卫生 公共卫生
- 行为科学 行为科学
背景情况:
- 持续吸烟会加剧癌症死亡率,并对治疗结果产生负面影响.
- 戒烟干预措施对于改善癌症患者的生存率和治疗疗效至关重要.
研究的目的:
- 对癌症患者的戒烟干预措施进行随机对照试验 (RCT) 的系统审查和元分析.
- 评估各种戒烟策略在改善癌症幸存者戒烟率方面的有效性.
主要方法:
- 在多个数据库 (PubMed,EMBASE,PsychINFO,CINAHL) 中对RCT进行系统审查.
- 使用柯克兰偏差风险评估工具2 (ROB-2) 进行偏差风险评估.
- 使用固定效应模型进行的元分析,最后一次搜索是在2025年3月.
主要成果:
- 涉及984篇出版物的23项研究符合纳入标准.
- 戒烟干预措施显著增加了戒烟率 (RR=1.36;95% CI:1.22-1.51).
- 生物化学验证的戒烟显示出比自我报告的戒烟 (RR=1.25;95% CI:1.09-1.42) 更强大的结果 (RR=1.57;95% CI:1.32-1.87).
结论:
- 强有力的证据支持癌症患者戒烟干预措施的有效性.
- 药理学和行为学方法的结合特别有效.
- 医疗保健提供者应鼓励癌症患者采用全面的戒烟策略.
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