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Updated: Jan 8, 2026

Making, Testing, and Using Potassium Ion Selective Microelectrodes in Tissue Slices of Adult Brain
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导电测量传感器用于离子分析,使用含有脂性盐的无毒离子选择性膜

Thiyagarajan Natarajan1, Tom Wade1, Anjana Ramesh Peringath1

  • 1Department of Materials Science, Device Materials Group, University of Cambridge, 27 Charles Babbage Road, Cambridge, CB3 0FS UK.

Journal of materials research
|December 22, 2025
PubMed
概括

一个新的,无毒的选择性电极 (K-III) 为导电计测量提供了更好的性能. 这种更安全的替代方案在生物分析应用中提高了检测的灵敏度和选择性.

关键词:
增材制造 增材制造是一种增材制造.添加剂 添加剂 添加剂电气性质 电气性质膜膜是一种膜.传感器 传感器 传感器

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Potentiometry: Membrane Electrodes01:15

Potentiometry: Membrane Electrodes

Membrane electrodes, also known as p-ion electrodes, use membranes that selectively interact with free analyte ions, generating a potential difference across the membrane. The resulting membrane potential, known as the asymmetry potential, is not zero even when analyte concentrations on both sides of the membrane are equal. The membrane's response is typically not selective to a single analyte but proportional to the concentration of all ions in the sample solution capable of interacting at...
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Potentiometry is an analytical technique that measures the potential difference between two electrodes in an electrochemical cell without drawing any significant current that could alter the solution's composition. This method employs an indicator electrode, which exchanges electrons with the analyte solution, and a reference electrode with a constant potential. Each electrode is immersed in a solution comprised of two half-cells. In a conventional setup, the reference electrode serves as...
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Potentiometry: Types of Electrodes

Reference electrodes serve as a stable reference point for potentiometric measurements, while indicator and working electrodes react to variations in the composition of a solution.
The Standard Hydrogen Electrode (SHE) is a widely used reference electrode that maintains zero potential across all temperatures. However, its need for a continuous hydrogen gas supply renders it impractical for everyday use.
An alternative to SHE is the Saturated Calomel Electrode (SCE). This electrode features an...
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Ion Channels01:19

Ion Channels

The movement of ions like sodium, potassium, and calcium into and out of the cell is essential to maintain the electrochemical gradient in living cells. The ion channels—a class of membrane transport proteins—help maintain this ionic gradient for the smooth functioning of physiological activities such as maintaining cell size and volume, conducting nerve impulses, and gas and nutrient exchange.
Ion channels are specialized integral membrane proteins on the plasma membrane that allow...
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Controlled-potential coulometry, also known as potentiostatic coulometry, employs a three-electrode system in which the working electrode's potential is precisely regulated using a potentiostat. Platinum working electrodes are utilized for positive potentials, while mercury pool electrodes are favored for extremely negative potentials. The platinum counter electrode is separated from the analyte using a membrane or salt bridge to avoid interference in the analysis.
The chosen potential...
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