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空间,转录和表观遗传学分析将背角神经元与慢性疼痛遗传倾向联系起来

Cynthia M Arokiaraj1, Michael J Leone2,3, Michael Kleyman2

  • 1Department of Neurobiology and Pittsburgh Center for Pain Research, University of Pittsburgh School of Medicine, Pittsburgh, PA, 15213.

bioRxiv : the preprint server for biology
|December 22, 2025
PubMed
概括

与慢性疼痛相关的遗传变异可能会影响背部角神经元. 这项研究整合了多个物种的数据,以确定与慢性疼痛敏感性相关的特定神经元亚型.

关键词:
在GWAS中,GWAS就是GWAS.rhesus macaque 是一个大猩猩.细胞类型 细胞类型慢性疼痛是一种慢性疼痛.人类 人类 人类 人类 人类 人类 人类这里是鼠标鼠标鼠标鼠标鼠标鼠标.多重化在现场混合化.一个单核的ATAC-seqq.单核RNA测序的一个核.空间转录学 空间转录学脊髓是指脊髓的部分.变种变种的变种

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