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血管表型中的表观遗传开关增加了抗瘤免疫力

Dae Joong Kim, Mitchell McGinty, Swetha Anandh

    bioRxiv : the preprint server for biology
    |December 22, 2025
    PubMed
    概括

    向内皮细胞中的DNA甲基转移酶1可以减少瘤血管的生长,并增强抗瘤免疫力. 这种表观遗传策略改善了T细胞的透和对癌症免疫治疗的反应.

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