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SLFN11将车放在替代延长端粒的车上

Prashant Khandagale, Allison L Welter, Shar-Yin Naomi Huang

    bioRxiv : the preprint server for biology
    |December 22, 2025
    PubMed
    概括

    施莱芬11 (SLFN11) 通过局部化到端粒来抑制端粒的替代延长 (ALT) 途径. SLFN11的丧失,以及ATRX/DAXX的失活,有助于癌症中ALT的激活.

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