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Updated: Jan 8, 2026

An In Vitro Assay to Detect tRNA-Isopentenyl Transferase Activity
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通过非典型的SPOUT甲基转移酶Trm10进行tRNA基质识别和修饰的分子基础

Suparno Nandi1, Sarah E Strassler1, Debayan Dey1

  • 1Department of Biochemistry, Emory University School of Medicine, Atlanta, Georgia, USA.

bioRxiv : the preprint server for biology
|December 22, 2025
PubMed
概括

Trm10甲基转移酶使用特定的相互作用来修改tRNA中的guanosin 9. 化EM结构揭示了Trm10如何结合tRNA,引导瓜诺辛进行甲基化,并显示了瓜诺辛对腺的选择性.

关键词:
SPOUT 甲基转移酶的使用方法甲基化处理的方法蛋白质-RNA识别功能这是一个tRNARNA.

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