反边的雅典和去中心的个性化球体圆柱形 (DISC) 协议的结果,用于角管理
Igor Knezović1, Nina Jovanović1, Sara Djurić1
1Knezović Eye Institute, Zagreb, Croatia.
GMS ophthalmology cases
|December 22, 2025
概括
与雅典协议相比,DISC协议在改善未经纠正和纠正的视力方面显示出优异的结果. 这种新的方法提供了一个有前途的策略,用于管理角的进展和增强视觉功能.
科学领域:
- 眼科医生 眼科 眼科
- 角膜外科手术 角膜外科手术
- 视觉科学 视觉科学 视觉科学
背景情况:
- 角膜是一种渐进的角膜脱落,导致不规则的眼和视力丧失.
- 目前的治疗方法旨在阻止进展并改善视力敏度,成功率各不相同.
研究的目的:
- 为了比较两个外科手术方案的疗效:去中心的个性化球体圆柱体 (DISC) 协议和雅典协议.
- 为了评估视力敏度,角膜不规则性和异常,这些不同的手术干预后.
主要方法:
- 一名患者在左眼接受了雅典协议 (光疗切除,部分拓导向光折射切除,角膜交叉链接) 和右眼接受了DISC协议 (光疗切除,DISC排卵细胞切除,角膜交叉链接).
- 两只眼睛都接受了标准化上皮质切除,利博弗拉应用和UVA角膜交叉链接 (CXL).
- 在36个月内评估了术后结果,包括未经校正的视敏度 (UCVA),最佳校正的视敏度 (BCVA) 和角膜拓分析 (弗里耶分析,泽尼克偏差).
主要成果:
- 36个月后,右眼 (DISC协议) 实现了UCVA和BCVA的20/22,而左眼 (雅典协议) 保持了手术前UCVA,BCVA为-3.5 Dsph=20/30.
- 里埃分析显示,右眼角膜不规则性减少了52%,而左眼则减少了12.8%.
- 泽尼克的分析显示,雅典协议的球形偏差增加较小,但DISC协议显示高度分散率下降更大,整体视觉效果有所改善.
结论:
- 与雅典协议相比,DISC协议在改善形患者的未经纠正和最佳纠正视力敏度方面似乎更有效.
- DISC 协议显示了减少角膜不规则性的巨大潜力,并为角膜管理提供了一个有希望的策略.
- 需要对更大患者队伍进行进一步的研究,以验证DISC协议的长期疗效和安全性.
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