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Updated: Jan 8, 2026

Application of CRISPR Interference CRISPRi for Gene Silencing in Pathogenic Species of Leptospira
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移动CRISPRi作为一种用于细胞内病原体Piscirickettsia salmonis基因操纵的工具

Javiera Ortiz-Severin1, Paulette Geoffroy1, Pamela Aravena1

  • 1Laboratorio de Bioinformática y Expresión Génica, Instituto de Nutrición y Tecnología de los Alimentos (INTA), Universidad de Chile, Santiago, Chile.

Applied and environmental microbiology
|December 22, 2025
PubMed
概括

一个新的移动CRISPRi系统使得Piscirickettsia salmonis中的基因沉默成为可能,这种基因是导致沙门菌皮性败血症 (SRS) 的原因. 这种工具有助于研究P. salmonis的毒性,并开发对这种重要的水产养殖病原体的治疗方法.

关键词:
铁路吸收调节器 铁路吸收调节器移动-CRISPRii可以帮助我们.鱼类病原体的病原体铁的平衡基因 铁的平衡基因

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