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Updated: Jan 8, 2026

Spatio-Temporal Manipulation of Small GTPase Activity at Subcellular Level and on Timescale of Seconds in Living Cells
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酸化会诱导改变的质子化状态,并以全学调节Rac1-RhoGDI复合体

Krishnendu Sinha1, Amit Kumawat2, Hyunbum Jang3

  • 1Department of Chemical and Biological Sciences, S. N. Bose National Centre for Basic Sciences, Kolkata, India.

Protein science : a publication of the Protein Society
|December 22, 2025
PubMed
概括

罗核酸解离抑制剂 (RhoGDI) 的特定位点酸化控制Rac1 GTPase的释放. 在Ser101/Ser174的双酸化通过改变质子化状态和破坏通信通路而使Rac1-RhoGDI结合异质弱化.

关键词:
这是一个GTPase.模拟MD的模拟方法罗格迪 (RhoGDI) 是一种艾洛斯特菌是所有菌的恒定的pH 值 MD MD酸化的方法是:光化.

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