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Updated: Jan 8, 2026

Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones
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Published on: February 7, 2019

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获取Pyrazolo[1,5-a]pyrimidinone Regioisomers 来自乙基化膜酸中的获取方法

Maxime Donzel1, Erik Chorell1

  • 1Department of Chemistry, Umeå University, SE 901 87 Umeå, Sweden.

Organic letters
|December 22, 2025
PubMed
概括

研究人员开发了两种高效的方法来合成pyrazolo[1,5-a]pyrimidinones使用3-aminopyrazoles和乙烯酸Meldrum的酸. 反应条件允许在高产量中选择性合成pyrazolo[1,5-a]pyrimidin-5-ones或-7-ones.

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