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骨内骨性伪癌性增生症:状细胞癌的一个组织学模仿

Jessica Jawhar¹, Gopi Voonna², Peter Sadow³

¹University of New England College of Osteopathic Medicine, Portland, ME, USA.

Head and neck pathology

|December 22, 2025

概括

伪癌细胞增生症可以模仿骨中状细胞癌,这构成了诊断挑战. 这种良性状况,在下腹病例中见到,需要仔细的组织学评估,以避免误诊.

科学领域:

口腔病理学口腔病理学
手术病理学手术病理学
在瘤学瘤学.

背景情况:

伪癌性增生症 (PCH) 是一种良性状增生症.
它可以在组织学上类似于分化良好的状细胞癌.
骨中的PCH存在诊断挑战,可能导致误诊.

研究的目的:

报告一个下内骨性伪癌性增生病例.
突出诊断挑战和差异性考虑.
强调准确诊断对于适当的患者管理的重要性.

主要方法:

一个65岁的老人下痛和的案例介绍.
临床差异诊断包括恶性瘤,骨髓缩和牙病变.
用P53免疫染色和GMSF染色对除菌样本进行组织学检查.

主要成果:

组织学揭示了骨髓内的多发性状上皮质.
发现包括急性骨髓炎,骨 necrosis,和Actinomyces生物体.
没有识别出状异型或恶性瘤特征;P53染色是野生类型.

结论:

该病例被诊断为下骨内骨性伪癌性增生症.
准确的识别对于防止误诊和过度治疗至关重要.
患者对相关骨髓炎的抗生素治疗反应良好.

关键词:

案例报告案例报告部骨髓缩症部骨髓缩部伪癌性瘤性增生症伪癌性状状增生症.伪表皮质瘤性增生症.

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