对18F-胆PET/CT的假阳性皮肤摄入与甲状腺腺瘤患者的炎症性表皮囊有关
Elske Quak1, Audrey Catroux2, Audrey Lasne-Cardon3
1Departments of Nuclear Medicine.
Clinical nuclear medicine
|December 22, 2025
概括
18F-胆PET/CT精确地定位了副甲状腺瘤,但也显示了由于炎症性表皮囊引起的假阳性皮肤吸收. 这凸显了副甲状腺成像中的潜在诊断挑战.
科学领域:
- 核医学是一种核医学.
- 在瘤学瘤学.
- 皮肤病学 皮肤病学
背景情况:
- 原发性甲状腺功能障碍症往往需要对甲状腺腺瘤进行手术定位.
- 18F-胆正子发射断层扫描/计算机断层扫描 (PET/CT) 越来越多地用于偏甲状腺腺瘤的局部化.
- 皮肤对PET/CT的吸收有时会导致误解.
研究的目的:
- 在患有原发性副甲状腺症的患者中报告一个假阳性18F-胆PET/CT皮肤吸收病例.
- 为了调查在甲状腺腺瘤局部化期间皮肤意外吸收的原因.
- 为了强调在皮肤上吸收18F-胆的差异诊断.
主要方法:
- 一名患有原发性副甲状腺功能障碍的70岁男性接受了18F-胆PET/CT用于手术规划.
- PET/CT扫描分析了副甲状腺腺瘤的局部化和任何异常吸收.
- 随后进行了手术切除和鉴定病变的组织病理学检查.
主要成果:
- 18F-胆PET/CT成功证实了右上侧甲状腺腺瘤.
- 扫描还揭示了左部地区意外的18F-胆皮肤吸收.
- 组织病理学证实皮肤吸收是由于一种炎症性表皮囊.
结论:
- 炎症性表皮质囊可以在18F-胆PET/CT上模仿瘤或瘤性副甲状腺组织.
- 对良性炎症状况的认识对于准确解释18F-胆PET/CT发现至关重要.
- 这一案例强调了将成像检测结果与临床表现相关联,并考虑差异诊断的重要性.
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