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Updated: Jan 8, 2026

Mapping Dysfunctional Protein-Protein Interactions in Disease
09:39

Mapping Dysfunctional Protein-Protein Interactions in Disease

Published on: October 24, 2025

510

蛋白质-蛋白质相互作用接口的多重映射

Jingxuan He1, Ling-Nan Zou1, Vidhi Pareek2

  • 1Department of Chemistry, The Pennsylvania State University, University Park, PA 16802.

Proceedings of the National Academy of Sciences of the United States of America
|December 22, 2025
PubMed
概括

我们开发了分裂抗生素耐药性补充 (SpARC-map),这是一种用于识别蛋白质-蛋白质相互作用 (PPI) 接口的新方法. 这种技术使用细菌宿主和DNA测序来绘制相互作用的地图,甚至是弱的,没有专门的设备.

关键词:
蛋白质复合体是一种蛋白质复合体.蛋白质相互作用接口接口.蛋白质蛋白质相互作用纯种类型的纯种类型

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