[肥胖和乳头甲状腺癌的超声波恶性特征之间的相关性]
1Department of Thyroid Surgery, China-Japan Union Hospital of Jilin University, Jilin Provincial Key Laboratory of Translational Medicine of Surgery, Jilin Provincial Engineering Laboratory of Thyroid Disease Prevention and Treatment, Changchun 130033, China.
Zhonghua yi xue za zhi
|December 22, 2025
概括
肥胖与较少的穿刺性超声波焦点有关,这是乳头甲状腺癌 (PTC) 的关键超声波标志. 这一发现特别在肥胖男性中被注意到,这表明肥胖可能会改变PTC.
科学领域:
- 在瘤学瘤学.
- 放射学 放射学是一门学科.
- 流行病学 流行病学
背景情况:
- 肥胖是一个日益严重的全球健康问题.
- 乳头甲状腺癌 (PTC) 是最常见的甲状腺癌类型.
- 了解肥胖和PTC超声波特征之间的关系对于诊断至关重要.
研究的目的:
- 为了研究肥胖与皮皮性甲状腺癌 (PTC) 中特定恶性超声波特征之间的关联.
- 为了比较超声波特征和甲状腺成像报告和数据系统 (TIRADS) 在肥胖和非肥胖PTC患者之间的得分.
- 分析肥胖和PTC超声波结果之间的相关性中的性别特异性差异.
主要方法:
- 对8,483名被诊断患有PTC的患者进行了回顾性分析.
- 患者分为非肥胖和肥胖 (BMI ≥28 kg/m2) 的两组.
- 倾向分数匹配 (PSM) 用于1:1匹配;采用多变量逻辑回归.
主要成果:
- 在PSM后,肥胖与PTC患者中点状超声焦点 (微) 的比例较低 (P=0.009).
- 与非肥胖男性相比,肥胖男性的明显低声结节和粗结节的发生率更高,但点状高声焦点的发生率较低 (P<0.05).
- 肥胖和非肥胖女性之间没有观察到超声波特征或TIRADS评分的显著差异 (P>0.05).
结论:
- 肥胖与点状超声波焦点的发病率降低有关,点状超声波焦点是PTC恶性瘤的关键指标.
- 肥胖和特定超声波特征之间的关联在性别之间存在差异,肥胖男性表现出不同的模式.
- 这些发现凸显了肥胖对乳头甲状腺癌超声波表现的潜在影响.
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