[分析设置错误及其与前列腺癌用不同固定装置进行图像引导放射治疗的临床因素的相关性]
Xuan Guo1,2, Yang Liu1, Yan Xiong1
1Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou 510060, China.
Nan fang yi ke da xue xue bao = Journal of Southern Medical University
|December 22, 2025
概括
定制的倾斜板在前列腺癌放射治疗中提供了卓越的设置精度,特别是在右-左和上-下方向. 对于淋巴结辐射或低BMI的患者来说,SI方向的设置精度至关重要.
科学领域:
- 辐射瘤学 辐射瘤学
- 医学物理 医学物理
- 前列腺癌治疗方法 前列腺癌治疗方法
背景情况:
- 前列腺癌的精确放射治疗需要精确的患者固定.
- 设置错误可能会损害治疗的有效性并增加毒性.
- 评估固定装置对于优化放射治疗精度至关重要.
研究的目的:
- 量化比较前列腺癌放射治疗中的四种固定装置的设置错误.
- 分析影响设置精度的因素,包括淋巴结辐射,年龄和BMI.
- 为精密放射治疗中选择最佳固定装置提供证据.
主要方法:
- 对240名接受图像指导放射治疗的前列腺癌患者的回顾性分析.
- 四种固定装置的比较:1.2米真空袋,1.8米真空袋,Orfit框架和定制的倾斜板.
- 在RL,SI和AP方向的设置错误使用圆光束CT (CBCT) 和XVI系统灰度记录进行测量.
主要成果:
- 在四种设备中观察到设置错误的显著差异 (P<0.05).
- 定制的倾斜板显示了最小的RL和SI错误,但更大的AP错误.
- 淋巴结辐射和较低的BMI与分别增加的AP和SI误差有关.
结论:
- 定制的倾斜板为前列腺癌放射治疗提供RL和SI方向的高设置精度.
- 系统的AP方向错误与倾斜板需要考虑.
- 对于淋巴结辐射或低BMI的患者来说,SI定向精度尤其重要,以指导设备选择和治疗优化.
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