接受选择性手术的可卡因尿检阳性患者的术后结果:系统性审查
Maximiliano Cardozo-Panoff1, Robert Blasco-Mariño2, Marcos De Miguel1
1Department of Anaesthesiology, Vall d'Hebron University Hospital, Barcelona, Spain.
Journal of clinical anesthesia
|December 22, 2025
概括
在选择性手术前对可卡因呈阳性测试的患者没有增加术后并发症. 然而,有限的证据需要进一步研究可卡因使用和手术风险.
科学领域:
- 麻醉学 麻醉学
- 心脏病学 心脏病学
- 药理学 药理学是指药理学的学科.
背景情况:
- 可卡因滥用是全球重要的健康问题,在欧洲尤为普遍.
- 选择性手术患者的可卡因尿液测试呈阳性,需要仔细评估术后风险.
研究的目的:
- 系统地审查接受可选手术的患者的术后结果,其尿液测试呈可卡因阳性.
- 评估手术前可卡因使用与手术并发症之间的关联.
主要方法:
- 在多个数据库 (MEDLINE,Embase,科学网,Scopus等) 中进行系统的文献搜索. ) 的情况.
- 使用纽卡斯尔-太华尺度进行质量评估.
- 根据PRISMA指南进行数据综合.
主要成果:
- 对3项研究 (707名患者) 的分析显示,可卡因阳性和阴性组之间的血液动力学事件没有显著差异.
- 在可卡因阳性患者中,增加了血管压缩剂和抗高血压剂的使用.
- 没有报告发生心律失常或死亡事件;可卡因阴性患者的手术持续时间更长.
结论:
- 根据目前有限的证据,接受选择性手术的无症状患者,可卡因测试呈阳性,并没有显示出更高的并发症率.
- 方法上的局限性 (回顾性设计,小样本,潜在偏差) 阻止了最终的结论.
- 进一步的前性研究对于澄清与可卡因使用相关的术后风险至关重要.
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