相关实验视频

Updated: Jan 8, 2026

Voluntary Breath-hold Technique for Reducing Heart Dose in Left Breast Radiotherapy

Voluntary Breath-hold Technique for Reducing Heart Dose in Left Breast Radiotherapy

Published on: July 3, 2014

揭示与乳腺放射治疗的急性和晚期乳腺副作用相关的区域,使用基于voxel-wise图像的数据挖掘分析

Tanwiwat Jaikuna¹, Fiona Wilson², Carmel Anandadas²

¹Division of Cancer Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Christie NHS Foundation Trust Hospital, Manchester, United Kingdom; Division of Radiation Oncology, Department of Radiology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

|December 22, 2025

概括

研究人员确定了特定的乳房区域,辐射疗法 (RT) 剂量与疼痛和胀等副作用相关. 这一发现可以帮助尽量减少接受RT的乳腺癌患者的不良影响.

科学领域:

在瘤学瘤学.
辐射瘤学辐射瘤学
医学物理医学物理

背景情况:

乳腺癌治疗,包括放射治疗 (RT),可能会导致严重的副作用,影响患者的生活质量.
确定毒性特征的特定剂量-体积关系对于优化RT规划至关重要.

研究的目的:

确定乳房内RT剂量与特定副作用相关的解剖区域.
使用基于图像的数据挖掘 (IBDM) 来识别剂量毒性相关性.

主要方法:

分析了922名接受RT后乳房保护手术的患者的数据.
剂量分布的空间规范化和转换为 2 Gy 分数中的等效剂量 (EQD2).
应用多变量顺序回归来评估从确定区域的剂量参数的意义.

主要成果:

在不同的乳腺象限中,确定了与乳腺副作用相关的重要区域.
与整个乳房轮相比,这些地区的平均EQD2较高,特别是2级+毒性.
从这些特定区域获得的剂量参数在多变量分析中被证明是重要的.

结论:

已经确定了乳房内的特定区域,其中局部RT剂量与副作用的发生相关.
这一发现为开发减少乳腺放射治疗后副作用的策略提供了一个新的假设.

关键词:

急性和晚期乳腺副作用乳腺放射疗法乳腺放射疗法基于图像的数据挖掘基于Voxel的分析

更多相关视频

Integrating Augmented Reality Tools in Breast Cancer Related Lymphedema Prognostication and Diagnosis

Integrating Augmented Reality Tools in Breast Cancer Related Lymphedema Prognostication and Diagnosis

Published on: February 6, 2020

Tracking the Mammary Architectural Features and Detecting Breast Cancer with Magnetic Resonance Diffusion Tensor Imaging

Tracking the Mammary Architectural Features and Detecting Breast Cancer with Magnetic Resonance Diffusion Tensor Imaging

Published on: December 15, 2014

相关概念视频

Radiological Investigation II: MRI and Ventilation Perfusion Scan

Radiological Investigation II: MRI and Ventilation Perfusion Scan

Description
Magnetic Resonance Imaging (MRI) and Ventilation Perfusion Scans are two radiological investigations that offer detailed diagnostic images of the body, particularly lung structures.
MRI
MRI uses magnetic fields and radiofrequency signals to distinguish between normal and abnormal tissues. This technology provides a more detailed diagnostic image than CT scans, enabling it to characterize pulmonary nodules, stage bronchogenic carcinoma, and evaluate inflammatory activity in...

Radiological Investigation III: Pulmonary Angiogram and PET Scan

Radiological Investigation III: Pulmonary Angiogram and PET Scan

Radiological investigations are paramount in the diagnosis and management of various pulmonary diseases. Two essential investigations are the Pulmonary Angiogram and the Positron Emission Tomography (PET) Scan.
Pulmonary Angiogram
A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...