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Updated: Jan 8, 2026

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由核受体RORγ调节的FGF1-FGFR2轴代表了在肝脏内胆管癌中有效的策略

Zhanfeng Gu1, Xiaojuan Wang2, Hong Wang3

  • 1Department of Hepatobiliary surgery, The Third Affiliated Hospital, Southern Medical University, Guangdong, 510630, Guangzhou, China.

Cell death discovery
|December 22, 2025
PubMed
概括

与视网膜相关的孤儿受体玛 (RORγ) 通过激活FGFR2信号来驱动肝内胆管癌 (iCCA) 的生长. 抑制RORγ对治疗iCCA和克服对向疗法的耐药性有希望.

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