在联合化疗和免疫检查点抑制剂治疗期间,与免疫相关的不良事件相关的独特免疫细胞动态

Lei Zhang1, Xiaokai Fan2,3, Jun Ma4

  • 1Department of Radiation Oncology, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.

Nature communications
|December 22, 2025
PubMed
概括

化学放射治疗和免疫治疗的结合会增加与免疫相关的不良事件 (irAEs). 这项研究揭示了irAE患者的T细胞升高和B细胞动态改变,特定的单细胞扩张和免疫细胞聚集在瘤中.

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