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Updated: Jun 12, 2026

Establishing a Mouse Model of a Pure Small Fiber Neuropathy with the Ultrapotent Agonist of Transient Receptor Potential Vanilloid Type 1
09:39

Establishing a Mouse Model of a Pure Small Fiber Neuropathy with the Ultrapotent Agonist of Transient Receptor Potential Vanilloid Type 1

Published on: February 13, 2018

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施瓦恩细胞Lrp1缺失通过调节线粒体功能和TRPV1/TRPA1活动来驱动三角神经元敏感化和口面疼痛

Zhiting Gong1,2, Morgan Zhang1,2, Naijiang Liu1,2

  • 1Translational Research Center, College of Dentistry, New York University, New York, NY, 10010, USA.

The journal of headache and pain
|December 22, 2025
PubMed
概括

施瓦恩细胞LRP1缺乏症通过损害线粒体功能和神经元-质通信而导致口腔面部疼痛. 这项研究强调了施万细胞是慢性疼痛的关键驱动因素,并将LRP1确定为潜在的治疗点.

关键词:
低密度脂蛋白受体相关蛋白1 (LRP1) 是一种低密度脂蛋白受体相关蛋白1.线粒体重塑 线粒体重塑面部或面部疼痛 面部疼痛施万的细胞细胞.在 TRPA1 中,在 TRPV1 中.

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