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Updated: Jan 8, 2026

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通过多层次调节cGAS,KAT2A会影响狼性炎的炎症进展

Youzhou Tang1, Ying Zhang2, Qingtai Cao2

  • 1Department of Nephropathy and Rheumatology, the 3rd Xiangya Hospital, Central South University, Changsha, 410013, Hunan, China.

Journal of molecular medicine (Berlin, Germany)
|December 22, 2025
PubMed
概括

酸乙转移酶2A (KAT2A) 在体外负面调节循环GMP-AMP合成酶 (cGAS),但在狼性炎模型中促进炎症. 一种抑制剂显示出保护作用,表明KAT2A在体内超出cGAS的点.

关键词:
在CGAS中,CGAS是最重要的.在KAT2A中,它是KAT2A狼性炎是一种神经炎.多级监管多层次的监管.

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