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垂体植入体刺激可以改善自我运动感知

B L Vermorken¹, S C J Van Boxel², B Volpe²

¹Department of Otorhinolaryngology and Head and Neck Surgery, Division of Balance Disorders, Mental Health and Neuroscience Research Institute (MHeNs), Maastricht University, Maastricht, The Netherlands. bernd.vermorken@mumc.nl.

European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery

|December 22, 2025

概括

这项研究表明,前体植入物 (VI) 刺激可以改善双侧前体病变 (BV) 患者的自我运动感知. 激发性刺激增强了曲线旋转的感知,为BV患者提供了更好的空间定向的潜力.

科学领域:

神经科学是一个神经科学.
耳鼻喉科耳鼻喉科耳鼻喉科
生物医学工程生物医学工程

背景情况:

双边前庭病变 (BV) 导致,不稳定,由于改变了自我运动感知而导致空间定向受损.
之前的研究表明,BV患者的感知自我运动值升高.
这项研究研究了多通道前庭植入物对自我运动感知值的影响.

研究的目的:

评估多通道前庭植入物 (VCI) 刺激对双侧前庭病变 (BV) 患者感知自我运动值的影响.

主要方法:

九名BV患者接受了试验性的内迷宫多通道VCI.
在三种条件下使用液压平台测量了转的感知自动运动值:VI OFF,VI ON (对称调制) 和VI ON (非对称调制).
旋转被分类为刺激性 (向植入侧) 或抑制性 (远离植入侧).

主要成果:

与没有刺激相比,垂体植入物 (VI) 刺激显著改善了激发性转动期间的感知自我运动值.
在激发性刺激期间观察到对称和不对称VI调制的改善.
对于抑制性转旋转没有发现显著改善,尽管对称调制显示出改善的趋势.

结论:

多通道前庭植入体刺激显示,它有望增强BV患者的方向特异性自我运动感知,特别是在起伏旋转方面.
刺激刺激对知觉的影响似乎比抑制刺激更为显著,与之前的前庭植入物研究一致.
垂体植入物为改善空间定向和减少双边垂体病变的症状提供了潜在的治疗途径.

关键词:

感知值是一个感知值.自动运动感知自动运动感知静脉前腔植入物是一种植入物.静脉口腔刺激的刺激

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