乳制品消费和心血管疾病风险:通过炎症生物标志物调解的多层次分析
Duoyu Ma1, Xinyi Cheng1, Qing Fang1
1The Second School of Clinical Medicine, Zhejiang Chinese Medical University, No. 548 Binwen Road, Hangzhou, 310053, Zhejiang, China.
Nutrition & metabolism
|December 23, 2025
概括
定期食用牛奶可能会降低心血管疾病 (CVD) 的风险,可能通过减少炎症. 增加牛奶摄入频率与更好的心脏健康结果有关,这表明公众健康有好处.
科学领域:
- 营养科学 营养科学
- 心血管健康 心血管健康
- 流行病学 流行病学
背景情况:
- 饮食中的乳制品摄入与心血管疾病 (CVD) 风险有关,但特定的产品关联需要进一步调查.
- 了解不同类型的乳制品,脂肪含量和消费频率对心血管疾病风险的影响对于公共卫生至关重要.
- 现有的研究尚未充分探索各种乳制品与心血管疾病结果之间的细微关系.
研究的目的:
- 评估不同乳制品类别,摄入频率和脂肪含量与心血管疾病 (CVD) 风险之间的关联.
- 使用大规模数据集调查乳制品摄入量与心血管疾病负担之间的全球关系.
- 探索乳制品-心血管疾病协会中的炎症标记物的潜在调解作用.
主要方法:
- 分析了全球乳制品摄入量数据 (1990-2018) 和心血管疾病负担指标 (发病率,流行率,DALYs).
- 来自30341名NHANES参与者的个人数据评估了乳制品消费和心血管疾病风险.
- 定向非循环图和因果调解模型检查了炎症标志物的作用 (SIRI,MLR,NLR).
主要成果:
- 在全球范围内,较高的牛奶消费与较低的心血管疾病 (CVD) 风险相关.
- 牛奶摄入量与心血管疾病,冠心病 (CHD) 和心脏病发作 (HA) 风险有负面关联.
- 炎症标志物 (SIRI,MLR,NLR) 部分调解了牛奶与心血管疾病的关联,每天或每周摄入的频率与心血管疾病风险降低有关.
结论:
- 牛奶的摄入可能会对心脏病,心脏病和HA产生保护作用,可能通过减轻炎症.
- 牛奶消费的频率是影响心血管疾病风险的重要因素.
- 在均衡饮食中促进定期摄入牛奶可以帮助降低全球心血管疾病负担.
相关概念视频
Blood Studies for Cardiovascular System II: CRP, Hcy, and Cardiac Natriuretic Peptide Markers
516
Cardiac biomarkers are critical in diagnosing, prognosing, and managing cardiovascular diseases. Routine measurement of specific biomarkers such as B-type natriuretic peptide (BNP), C-reactive protein (CRP), and homocysteine (Hcy) is common practice in clinical settings to evaluate heart function and predict cardiovascular events.
These markers indicate stress or strain on the heart muscle:
Natriuretic Peptides (BNP)
Cardiac myocytes produce these hormones in response to ventricular stretching...
These markers indicate stress or strain on the heart muscle:
Natriuretic Peptides (BNP)
Cardiac myocytes produce these hormones in response to ventricular stretching...
516
Coronary Artery Disease I: Introduction
846
Coronary Artery Disease (CAD): An Overview with Scientific InsightsCoronary Artery Disease (CAD), often referred to as C-A-D, is a prevalent blood vessel disorder classified under the broader category of atherosclerosis. Atherosclerosis is a pathological process characterized by the hardening and narrowing of arteries due to the accumulation of atherosclerotic plaques. These plaques are composed of cholesterol, fatty substances, inflammatory cells, calcium, and fibrin, reducing blood flow to...
846
Atherosclerosis III: Management
291
Management of atherosclerosis involves an integrated strategy encompassing pharmacological treatment, surgical interventions, lifestyle changes, and nutrition therapy to address the multifactorial nature of the disease.Pharmacological TherapyA cornerstone of atherosclerosis management is the use of pharmacological agents. Statins, such as atorvastatin, are pivotal in inhibiting HMG-CoA reductase, an enzyme that catalyzes an initial step in cholesterol synthesis in the liver. This reduction in...
291
Blood Studies for Cardiovascular System I: Cardiac Biomarkers
749
Cardiac biomarkers are enzymes, proteins, and hormones released into the blood when cardiac cells are injured. They are powerful tools for triaging.
The essential diagnostic tools for detecting myocardial necrosis and monitoring individuals suspected of having acute coronary syndrome (ACS) include:
Troponins
Troponins, particularly cardiac troponins I and T, are the most precise and sensitive markers of myocardial injury. They are detectable within 4-6 hours of myocardial injury and remain...
The essential diagnostic tools for detecting myocardial necrosis and monitoring individuals suspected of having acute coronary syndrome (ACS) include:
Troponins
Troponins, particularly cardiac troponins I and T, are the most precise and sensitive markers of myocardial injury. They are detectable within 4-6 hours of myocardial injury and remain...
749
Psychoneuroimmunology: Cardiovascular Disease
367
Psychoneuroimmunology (PNI) is a multidisciplinary field that examines how psychological factors, particularly stress, interact with the immune system and impact physical health. Research in PNI has shown that chronic or traumatic stress can disrupt both the hypothalamic-pituitary-adrenal axis and the sympathetic nervous system. These disruptions contribute to serious health conditions, including cardiovascular diseases.
A key area of focus in PNI is the relationship between stress and coronary...
A key area of focus in PNI is the relationship between stress and coronary...
367
Cholesterol: Significance and Regulation
1.2K
Although not a source of energy, cholesterol plays a significant role as a foundational structure for bile salts, steroid hormones, and vitamin D, as well as being a crucial component of plasma membranes. Approximately 15% of blood cholesterol is derived from our diet, with the remainder synthesized from acetyl CoA by the liver and intestines. Cholesterol is eliminated from the body through its conversion into bile salts, which are eventually discarded in the feces.
Considering cholesterol and...
Considering cholesterol and...
1.2K


