谷物摄入量与前列腺特异性抗原之间的关联:美国男性的横截面研究
Hongbo Xie1, Senlin Wang2, Yunan Liang1
1Department of Urology, National Key Specialty of Urology, Tianjin Institute of Urology, The Second Hospital of Tianjin Medical University, Tianjin, China.
Medicine
|December 23, 2025
概括
全谷物摄入量与较低的前列腺特异性抗原 (PSA) 水平有关,这表明它对前列腺健康起着保护作用. 在这项研究中,精制谷物摄入量与PSA水平没有显著的关联.
科学领域:
- 营养与饮食学 营养与饮食学
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 公共卫生 公共卫生
背景情况:
- 关于谷物消费和前列腺特异性抗原 (PSA) 水平存在不一致的发现.
- 前列腺健康是一个重大问题,PSA水平是关键生物标志物.
研究的目的:
- 调查全谷物和精制谷物摄入量与血清PSA水平之间的关联.
- 为了澄清饮食谷物模式和前列腺健康指标之间的关系.
主要方法:
- 国家健康和营养检查调查 (NHANES) 数据 (2001-2010) 的横截面分析.
- 包括5639名40岁及以上的男性参与者,具有完整的PSA测量和饮食摄入数据.
- 用多变量加权线性回归模型来评估关联.
主要成果:
- 在全谷物摄入量和血清PSA水平之间发现了显著的反向关联 (总P=0.0294).
- 在连续或分类分析中,精制谷物摄入量与PSA水平没有显著的关联 (所有P > .05).
- 全谷物和PSA之间的反向关联在各种人口和健康子组中是一致的.
结论:
- 全谷物消费可能有助于维持前列腺平衡,由较低的PSA水平表明.
- 强调全谷物的饮食建议可能对前列腺健康管理和预防策略有益.
- 进一步的研究可以探索全谷物对前列腺的潜在保护作用背后的机制.
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