终身血压水平,38年跟踪和高血压的预测
Fiia Iiskala1,2,3, Yaxing Meng4,5, Markus Juonala3,6
1Research Centre of Applied and Preventive Cardiovascular Medicine University of Turku Finland.
Journal of the American Heart Association
|December 23, 2025
概括
儿童高血压 (BP) 可以追踪到成年期,增加高血压的风险. 从6岁到12岁的长期累积高血压暴露显著提高了女性和男性的成人高血压风险.
科学领域:
- 心脏病学 心脏病学
- 儿科 儿科 儿科
- 公共卫生 公共卫生
背景情况:
- 儿童高血压 (BP) 是成人高血压的预测因素.
- 从童年开始持续暴露于高血压会增加长期心血管风险.
研究的目的:
- 为了检查儿童高血压的追踪到成年后的38年.
- 评估儿童累积高血压暴露与成人高血压风险之间的关联.
主要方法:
- 利用了来自年轻芬兰人研究 (YFS) 队列的数据 (N=3596,在基线时3-18岁).
- 在平均38.0年的随访期间重复测量血压.
- 定义的累积BP暴露使用曲线下的面积;高血压通过BP值,药物使用或医生诊断来定义.
主要成果:
- 儿童和成人血压之间观察到的弱相关性 (r=0.298女性,r=0.187男性).
- 长期累积升高的血压 (6-12岁) 显著增加了成人高血压风险 (HR 3.85女性,HR 2.66男性).
结论:
- 在儿童/青少年时期长期累积暴露于高血压与显著增加成人高血压风险有关.
- 早期血压监测和干预对于预防成人高血压至关重要.
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